The Relational Learning-based Extension (RLE) system predict Reactome pathway associations through a function prediction and relational learning approach. RLE relies mainly on combinations of simple properties from sequence features and some interaction network (protein-protein interactions and protein complexes).

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Beatriz García-Jiménez, Tirso Pons, Araceli Sanchis, Alfonso Valencia. Predicting Protein Relationships to Human Pathways through a Relational Learning Approach based on Simple Sequence Features. (Submitted)